Regenerative Medicine

Dezawa MuseCells™

Our revolutionary DEZAWA MUSE Cells™ are a next‑generation breakthrough in regenerative medicine: a rare, stress‑resistant subset of pluripotent mesenchymal stem cells naturally present in tissues such as bone marrow, adipose tissue, skin, and umbilical cord. Discovered in 2010 by Professor Mari Dezawa, they offer uniquely broad regenerative capacity without the risks commonly associated with pluripotent stem cells.

Because they express SSEA‑3 and survive severe stress (e.g. low‑nutrient, oxidative environments), DEZAWA MUSE Cells™ can home directly to sites of tissue damage and differentiate into multiple cell types in vivo, far exceeding the abilities of conventional MSCs.

Why Choose Dezawa MuseCells™ Over MSCs?

In contrast to standard MSC therapies, DEZAWA MUSE Cells™™:

Differentiate into most cell types in the body
Achieve direct tissue replacement rather than merely signaling for repair
Maintain excellent safety with no tumorigenic risk and no requirement for immunosuppression

At Neorgana, these stress‑resilient, pluripotent cells form the core of our regenerative treatments—enabling whole‑body rejuvenation, long‑lasting tissue renewal, and safer, more effective healing.

Key Benefits of DEZAWA MUSE CELLS™:

True tissue regeneration: Capable of spontaneous differentiation into a wide variety of cell types—from nerves to liver to skin—resulting in direct replacement of damaged tissue.
Targeted homing and repair: Naturally migrate to injury sites (via S1P‑S1PR2 signaling) and integrate into tissues for precise repair .
High stress resistance: Survive harsh environments (e.g. oxidative stress, nutrient deprivation) where traditional MSCs fail.
Safety and immunocompatibility: Non‑tumorigenic, no teratoma formation, and transplantable without immunosuppression due to HLA‑G expression and intrinsic anti‑immune mechanisms.
Superior delivery efficiency: Achieve ~15% targeted delivery to damaged organs after intravenous infusion, compared to <1% for traditional MSCs.
Pleiotropic therapeutic effects: Promote angiogenesis, anti‑inflammation, anti‑fibrosis, and long‑term survival in target tissues.
Clinically validated potential: Demonstrated efficacy in preclinical and early clinical settings across indications such as stroke, myocardial infarction, autoimmune conditions, chronic wounds, liver damage, neurodegeneration, and dermatological healing.

Distribute broadly through intravenous delivery and preferentially accumulate in damaged organs (~15% delivery rate vs <1%).

Natural Killer (NK) Cell Therapy

Immune precision for longevity and cellular cleansing

Neorgana’s NK Cell Therapy utilizes Natural Killer cells capable of accurately detecting and eliminating viruses, abnormal cells, and precancerous lesions.

In addition, they target and remove senescent “zombie” cells—key contributors to organ deterioration and chronic inflammation—helping restore immune balance and slow biological aging.

Key Benefits:

High-purity cellular therapy
Removal of aged and damaged cells
Enhanced immune resilience
Active prevention of age-related decline

A preventive and regenerative therapy designed to support your longevity.

Biological Precision for Cellular Renewal and Systemic Vitality

Peptide therapy uses specific chains of amino acids that act as molecular signals to repair tissues, modulate hormones, balance the immune system, and optimize metabolism.

Key Benefits:

Accelerates cellular repair and regeneration
Increases energy and mitochondrial function
Strengthens immune response
Regulates metabolism and supports muscle mass
Enhances skin tone, mental clarity, and overall systemic well-being

A fundamental tool in longevity medicine to restore biological balance from within.